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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21700 | NOS-IN-1 | 2-Imino-4-methylpiperidine (acetate) | NOS |
NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, and 1.1μM for human iNOS (hiNOS), hnNOS and heNOS, respectiv... | |||
T37696 | NOS1-IN-1 | nNOS Inhibitor I | NOS |
NOS1-IN-1(nNOS Inhibitor I) is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).NOS1-IN-1 has a Ki value of 39 μM for eNOS and 325 μM for iNOS.NOS1-IN-1 can be used for the study of neurological disorde... | |||
T0825 | Ebselen | SPI-1005,PZ-51,CCG-39161 | Phosphatase , Virus Protease , Calcium Channel , COX , HIV Protease |
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b... | |||
T61426 | NOS-IN-2 | ||
NOS-IN-2 (Compound 4i), an imidamide-derived NOS inhibitor, exhibits high potency and selectivity, specifically inhibiting iNOS with an IC50 of 20 μM while sparing eNOS. Demonstrating minimal toxicity, it is suitable for... | |||
T73353 | NOS-IN-3 | ||
NOS-IN-3 is a potent, selective, imidamide derived NOS inhibitor with an IC 50 against iNOS of 4.6 µM, without inhibiting eNOS . NOS-IN-3 has little toxicity and can be studied in the treatment of inducible isoform invo... | |||
T78229 | Aminoguanidine hemisulfate | Reactive Oxygen Species | |
Aminoguanidine hemisulfate, an inhibitor of nitric oxide synthases (NOS) and reactive oxygen species (ROS), effectively suppresses ANE-induced ROS production in vitro and is utilized in cancer research [1]. | |||
T82251 | GW274150 dihydrochloride | NO Synthase | |
GW274150 (dihydrochloride) is a potent, selective inhibitor of human and rat inducible nitric oxide synthase (iNOS), exhibiting oral activity and NADPH-dependence with an IC50 of 2.19 μM and Kd of 40 nM for human iNOS, a... | |||
T36777 | Thrombin Receptor Agonist Peptide (trifluoroacetate salt) | ||
Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. It induces aggregation of washed platelets as well as platelets in citrated and hirudin plasma. TRAP-14 (100 μM) ... | |||
T37270 | 9(E),11(E)-12-nitro Conjugated Linoleic Acid | ||
9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combinat... | |||
T37235 | (±)16(17)-EpDPA | (±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA | |
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de... | |||
T75339 | Methylene blue hydrate | ||
Methylene Blue (Basic Blue 9) hydrate functions as an inhibitor of guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS). This compound, known for its vasopressor activity, is widely utilized as a dy... |